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KMID : 0357919990330070537
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Korean Journal of Pathology
1999 Volume.33 No. 7 p.537 ~ p.539
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Balloon Cell Malignant Melanoma - A case report -
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Seo Ji-Young
Kim Soon-Young
Kang Jeong-Hee
Kim Young-Ok
Huh Bang
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Abstract
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Balloon cell malignant melanoma (BCMM) is a rare histologic variant of malignant melanoma, which is composed either predominantly or entirely of large clear or foamy cells. The incidence of balloon cell malignant melanoma is about 0.15% of all cutaneous malignant melanomas. Recently, we experienced a case of cutaneous balloon cell malignant melanoma in the right lower abdomen with right inguinal and both axillary lymph node metastasis in a 56-year-old man. The cutaneous lesion was 4.5 3.5 cm in size, a well-demarcated black nodular mass, involving abdominal skin and subcutaneous tissue. The tumor was histologically composed of two types of tumor cells: predominant clear cell and focal, pigmented spindle cell. The nodal lesion was composed entirely of clear cells. Both clear and spindle cells showed positive reaction for S-100 protein and HMB-45 on immunohistochemistry.
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KEYWORD
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Malignant melanoma, Balloon cell
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